Mayo Clinic announces 2019 Discovery Science Award recipients
The Mayo Clinic Center for Biomedical Discovery announced 2019 Discovery Science Award recipients. These awards fund teams working on innovative, cutting-edge discovery science with a focus on understanding biological processes that contribute to human disease.
“Understanding How UCH-L1 Regulates mRNA Translation in the B-Cell Development and B-Cell Lymphomagenesis”
Department of Pediatric and Adolescent Medicine and subspecialties
Paul Galardy, M.D. (PDHO ’06)
“Leukemic Extracellular Vesicles Modulate Chimeric Antigen Receptor T-Cell Immunotherapy”
“Elucidating the Mechanisms Through Which HP1a Contributes to Colon Cancer Metastasis”
Principal investigator: Hu Li, Ph.D. (MPET ’13), Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic Rochester
Co-investigators: Martin Fernandez-Zapico, M.D. (GI ’02), Division of Medical Oncology, Department of Oncology; Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic Rochester
Steven Offer, Ph.D. (MPET ’13), Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic Rochester
“Novel Mechanisms of pH-Mediated Metabolic Reprogramming in Type 2 Diabetes Mellitus”
Principal investigator: Aleksey Matveyenko, Ph.D. (PHYS ’14), Department of Physiology and Biomedical Engineering; Division of Endocrinology, Diabetes, Metabolism, & Nutrition, Department of Medicine, Mayo Clinic Rochester
Co-investigators: Michael Romero, Ph.D. (PHYS ’06), Department of Physiology and Biomedical Engineering; Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic Rochester
Taro Hitosugi, Ph.D. (ONCL ’13), Department of Molecular Pharmacology and Experimental Therapeutics; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic Rochester
“Understanding Hydrogen Sulfide Signaling in Neonatal Airway Disease”
“Stearoyl-COA Deasaturase-Mediated Fatty Acid Metabolism Controls B Cell Differentiation”
Principal investigator: Hu Zeng, Ph.D. (RS ’17), Division of Rheumatology, Department of Medicine; Department of Immunology, Mayo Clinic Rochester
Co-investigators: John Copland II, Ph.D. (CBS ’03), Department of Cancer Biology, Mayo Clinic Florida
Ian Lanza, Ph.D. (ENDO ’09, CTSA ’13), Division of Endocrinology, Diabetes, Metabolism, & Nutrition, Department of Medicine; Department of Physiology and Biomedical Engineering, Mayo Clinic Rochester
Uma Thanarajasingam, M.D., Ph.D. (IMM ’08, MDPH ’08, I ’11, CMR ’12), Division of Rheumatology, Department of Medicine, Mayo Clinic Rochester
Mariam Alexander, M.D. (APATH ’12), Division of Anatomic Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic Rochester