Mayo Clinic announces Advance the Practice Research Awards

Mayo Clinic announced recipients of 2019 Advance the Practice Research Awards. Criteria for selection of projects include medical need and commercialization potential. Other important include readiness for translation, impact on clinical practice, and strength of the research team and its collaborators.

The 17 winning projects were selected from among 56 submitted. Each winning project receives an award of up to $50,000 as well as project management and subject matter expertise from Center for Clinical and Translational Science (CCaTS) Office of Translation to Practice. The projects will address unmet clinical needs of patients through the development of novel therapeutics, devices, diagnostics or other products; or through the development and implementation of novel practice initiatives.

The awards are an initiative of the Office of Translation to Practice, in collaboration with Mayo Clinic Venture, research leadership in Arizona and Florida, the Department of Medicine and Department of Orthopedic Surgery in Rochester, and the Department of Surgery in Arizona.

“We’d like to thank our partners for their support of the 2019 APRA program and especially thank the dozens of investigators who took the time to submit their innovative proposals for consideration,” said Andrew Badley, M.D. (I ’94, INFD ’97), director of the Office of Translation to Practice. “The teams that were successful in this round represent some of the best and brightest at Mayo, and the projects they propose have a high chance of meaningfully impacting our patients and our practice.”

2019 Advance the Practice Research Award recipients

“Development of a Bidirectional-Deflectable, Irrigated Balloon Catheter for Electroporation”

“Perioperative Surgical Home”

Principal investigator: Dennis Bierle, M.D. (I ’16), Division of General Internal Medicine, Department of Medicine, Mayo Clinic Rochester

Collaborators: Karna Sundsted, M.D. (I ’13), Division of General Internal Medicine, Department of Medicine, Mayo Clinic Rochester

Adam Jacob, M.D. (I-1 ’03, ANES ’06, REG ’08, CTSC ’11), Department of Anesthesiology and Perioperative Medicine, Mayo Clinic Rochester

Karen Mauck, M.D. (ADGM ’01, CLRSH ’03), Division of General Internal Medicine, Department of Medicine, Mayo Clinic Rochester

David Danielson, M.D. (ANES ’81), Division of Multispecialty Anesthesia, Department of Anesthesiology and Perioperative Medicine, Mayo Clinic Rochester

Dennis Regan, M.D. (GIM ’16), Division of General Internal Medicine, Department of Medicine, Mayo Clinic Rochester

“Extraforaminal Dorsal Root Ganglion Stimulation for Pain Management”

Principal investigator: Mohamad Bydon, M.D. (NS ’15), Department of Neurologic Surgery, Mayo Clinic Rochester

“Motion Analysis Following Cerebrospinal Fluid Shunting for Idiopathic Normal Pressure Hydrocephalus”

Benjamin Elder, M.D., Ph.D. (NS '17)
Helene Houle Career Development Award in Neurologic Surgery Research
"A Novel Regenerative Engineered Implant for Enhancement of Spinal Fusions and Treatment of Large Bone Defects in the Spine and Extremities"
Department of Neurologic Surgery
Department of Physiology and Biomedical Engineering
Mayo Clinic in Rochester

“Transcatheter Anterior Mitral Leaflet Cutter”

Principal investigator: Mayra Guerrero, M.D. (CVIC ’18), Division of Interventional Cardiology, Department of Cardiovascular Medicine, Mayo Clinic Rochester

“Ergonomic Risk and Real-Time Guidance Outerwear (ERRGO) Development for Surgeons”

Principal investigator: Susan Hallbeck, Ph.D. (HCPR ’13), Department of Health Sciences Research; Department of Surgery, Mayo Clinic Rochester

Collaborators: Samuel Money, M.D. (VASS ’06), Division of Vascular and Endovascular Surgery, Department of Surgery, Mayo Clinic Arizona

Melissa Morrow, Ph.D. (BME ’09, OR ’12, CTSA ’13), Division of Health Care Policy and Research, Department of Health Sciences Research, Mayo Clinic Rochester

“Development of GM-CSF Deficient CART19 Cells as a Novel Therapeutic Option in B Cell Malignancies”

Principal investigator: Saad Kenderian, M.B., Ch.B. (HEMO ’13), Division of Hematology, Department of Medicine; Department of Molecular Medicine; Department of Immunology, Mayo Clinic Rochester

Collaborator: Stephen Russell, M.D., Ph.D. (MMED ’98), Department of Molecular Medicine; Division of Hematology, Department of Medicine, Mayo Clinic Rochester

“Optimization of HIV Clinic Workflow With LPN Support”

Principal investigator: Maryam Mahmood, M.B., Ch.B. (INFD ’18), Division of Infectious Diseases, Mayo Clinic Rochester

Collaborator: Stacey Rizza, M.D. (MED ’95, I ’98, INFD ’01), Division of Infectious Diseases, Mayo Clinic Rochester

“KIAA1199 Antibody for Mesothelioma and Other Aggressive Malignancies”

Principal investigator: Aaron Mansfield, M.D. (I ’09, CI ’11, HEMO ’13), Division of Medical Oncology, Department of Oncology, Mayo Clinic Rochester

Collaborator: Tobias Peikert, M.D. (THDCC ’07), Division of Pulmonary and Critical Care Medicine, Department of Medicine; Department of Molecular Medicine; Department of Immunology, Mayo Clinic Rochester

“Manufacturing Fibrin Scaffolds for RPE Transplantation”

Principal investigator: Alan Marmorstein, Ph.D. (OPH ’13), Department of Ophthalmology, Mayo Clinic Rochester

Collaborators: Raymond Iezzi, M.D. (OPH ’09), Department of Ophthalmology, Mayo Clinic Rochester

Jose Pulido, M.D. (OPH ’04), Department of Ophthalmology, Department of Molecular Medicine, Mayo Clinic Rochester

Timothy Olsen, M.D. (OPH ’16), Department of Ophthalmology, Mayo Clinic Rochester

“Pediatric Vertebral Body Anterior Tethering System”

Principal investigator: Todd Milbrandt, M.D. (OR ’16), chair, Division of Pediatric Orthopedics, Department of Orthopedic Surgery; Department of Physiology and Biomedical Engineering, Mayo Clinic Rochester

Collaborator: A. Noelle Larson, M.D. (OR ’09), Department of Orthopedic Surgery, Mayo Clinic Rochester

“Discovery of the Therapeutic Properties of Nucleotide Sugar Therapy Supplemented in Specific Ratios as a Novel Treatment of Congenial Disorders of Glycosylation”

Principal investigator: Eva Morava-Kozicz, M.D., Ph.D. (SC ’17), Department of Clinical Genomics, Mayo Clinic Rochester

Collaborators: Tamas Kozicz, M.D., Ph.D. (SC ’17), Department of Clinical Genomics, Department of Biochemistry and Molecular Biology, Mayo Clinic Rochester

Kimiyo Raymond, M.D. (LABM ’07), Division of Laboratory Genetics and Genomics, Department of Laboratory Medicine and Pathology, Department of Clinical Genomics, Mayo Clinic Rochester

“Point-of-Care Technology for Tailoring Asthma Treatment”

Principal investigator: Matthew Rank, M.D. (AIM ’08), chair, Division of Allergy, Asthma, and Clinical Immunology, Department of Internal Medicine; Division of Otolaryngology – Head & Neck Surgery/Audiology, Mayo Clinic Arizona

Collaborator: Elizabeth Jacobsen, Ph.D. (BIOC ’09), Division of Allergy, Asthma, and Clinical Immunology, Department of Internal Medicine, Mayo Clinic Arizona

“Implementation of Kidney Failure Risk Equation in Primary Care to Promote Evidence-Based Best Practice and Timely Referral to Nephrology for High-Risk Patients”

Principal investigator: Bjoerg Thorsteinsdottir, M.D. (I ’05), Division of Community Internal Medicine, Department of Medicine, Mayo Clinic Rochester

Collaborators: Nilay Shah, Ph.D. (S ’14), chair, Division of Health Care Policy and Research, Department of Health Sciences Research, Mayo Clinic Rochester

Celia Kamath, Ph.D. (HSR ’00), Department of Health Sciences Research, Mayo Clinic Rochester

Aaron Leppin, M.D. (ENDO ’14, CTSA ’16), Department of Health Sciences Research, Mayo Clinic Rochester

Robert Albright Jr., D.O. (I ’95, CCMI ’97, NEPH ’98), Division of Nephrology and Hypertension, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic Rochester

Rajeev Chaudhry, M.B.B.S. (CIM ’00), Division of Community Internal Medicine, Department of Cardiovascular Medicine, Mayo Clinic Rochester

“Minimally Invasive Cortical Neurosurgery Tools and Electrodes”

Principal investigator: Jamie Van Gompel, M.D. (CI ’11, NS ’12), Department of Neurologic Surgery, Department of Otorhinolaryngology – Head and Neck Surgery, Mayo Clinic Rochester

Collaborators: Gregory Worrell, M.D., Ph.D. (I-1 ’97, N ’00, NPHY ’01), Department of Neurology, Department of Physiology and Biomedical Engineering, Mayo Clinic Rochester

Sanjeet Grewal, M.D. (NS ’20), Department of Neurologic Surgery, Mayo Clinic Florida

“Epigenetic Bone Anabolic Drugs (‘Epibolics’) for Bone Regeneration”

Principal investigator: Andre van Wijnen, Ph.D. (OR ’16), Department of Orthopedic Surgery, Department of Physiology and Biomedical Engineering, Department of Biochemistry and Molecular Biology, Mayo Clinic Rochester

Collaborator: Amel Dudakovic, Ph.D. (OR ’15), Department of Orthopedic Surgery, Mayo Clinic Rochester

“Evaluation of the Mayo Clinic Synthetic Bone Scaffold #1 (MCSBS1) for Phase 1 Clinical Trial Applications”

Principal investigator: Michael Yaszemski, M.D., Ph.D. (OR ’96), Department of Orthopedic Surgery, Department of Physiology and Biomedical Engineering, Mayo Clinic Rochester

Collaborator: Alan Miller II, Ph.D. (RS ’12), Department of Orthopedic Surgery, Mayo Clinic Rochester

 

 

 

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