Mayo Clinic Center for Clinical and Translational Science & Center for Biomedical Discovery announce CCaTS-CBD Pilot Awards for Team Science

The Mayo Clinic Center for Clinical and Translational Science (CCaTS) and Center for Biomedical Discovery (CBD) announced recipients of the 2019 CCaTS-CBD Pilot Awards for Team Science. The goal of the awards is to enhance team science and develop clinical-basic partnerships in projects that have potential to impact clinical practice at Mayo Clinic.

Aleksandar Denic, M.D., Ph.D. (N '07, NBD '11, N '12)
Division of Nephrology and Hypertension
Department of Medicine
Mayo Clinic in Rochester
"NMR Profiling of Urine and Plasma in Rare Kidney Stone Patients": identifying novel metabolic biomarkers or metabolic profiles in urine and plasma of patients with rare kidney stone diseases

Jason Doles, Ph.D. (BMB '17)
Department of Biochemistry and Molecular Biology
Mayo Clinic in Rochester
"Modeling Pediatric Myopathies Using iPSC-Derived Skeletal Muscle Cells": creating novel models of early-onset muscle disease by generating muscle cells from patient-derived induced pluripotent stem cells

Hirohito Kita, M.D. (IMM '91)
Division of Allergic Diseases
Department of Medicine
Mayo Clinic in Rochester
"Effects of Preterm Birth on Lung Disease and Innate Immunity Late in Life": identifying the cytokine responses of blood innate lymphoid cells analysis in asthma development in children born preterm

A. Noelle Larson, M.D. (OR '09)
Department Orthopedic Surgery
Mayo Clinic Rochester
"Local Drug Delivery to the Spine to Augment Anterior Vertebral Body Tethering: A Fusionless, Minimally Invasive Surgery for Scoliosis": developing local drug delivery to augment anterior vertebral body tethering surgery to allow more children to be eligible for the procedure

Kay Medina, Ph.D. (IMM '05)
Department of Immunology
Mayo Clinic in Rochester
"The Role of miR-204 in Human Pediatric Pre-B Acute Lymphoblastic Leukemia": determiing expression levels of miR-204 in normal human BM hematopoietic progenitors and B cell precursor subsets and if sustained expression impairs normal B cell development

Scott Nyberg, M.D., Ph.D. (S '96)
Division of Transplantation Surgery
Department of Surgery
Mayo Clinic in Rochester
"Expanding and Purifying Human Hepatocytes with Congenital Metabolic Disorders: A Novel Therapeutic Approach for Pediatric Liver Diseases": developing a protocol to expand human hepatocytes in an immunodeficient pig "incubator," purify the with advanced cell sorting techniques and prepare them for gene correction and autologous transplant

Alexander Revzin, Ph.D. (PHYS '16)
Department of Physiology and Biomedical Engineering
Mayo Clinic in Rochester
"A Microfluidic Device for Blood Analysis in Neonates": demonstrating detection of c-reative protein and bilirubin, biomarkers relevant to neonatal monitoring, from a sub-microliter volume of blood

Lisa Schimmenti, M.D. (CGEN '15)
Chair, Department of Clinical Genomics
Mayo Clinic in Rochester
"Functional Variant Determination in Undiagnosed Disease Patients with Hearing Loss": identifying novel genes/variants that cause conditions characterized by hearing loss

 

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